Hamas and the Houthis vow retaliation for U.S. strikes on Iran, as reaction from most world leaders focuses on dialogue and deescalation.

Iran would likely struggle to repair or reconstitute its nuclear program while Israeli and U.S. warplanes are circling overhead. But it could still decide to fully end its cooperation with the International Atomic Energy Agency and abandon the the Nuclear Nonproliferation Treaty.

After initially favoring diplomacy, US President Donald Trump resorted to an extraordinary use of force against Iran on Saturday night, striking three of the regime’s key nuclear sites.