For patients with moderate to severe asthma, blockade with itepekimab, a new human IgG4P monoclonal antibody against the upstream alarmin interleukin-33, led to a reduction in events that indicate ...

Activation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Researchers at the Keck School of Medicine, University ...

Researchers at the Keck School of Medicine of the University of Southern California have discovered that a protein called Piezo1 prevents type 2 innate lymphoid cells (ILC2s) in the lung from becoming ...

BOSTON -- Patients with severe, uncontrolled asthma had significantly higher odds of improvement in asthma-related sleep disturbances and improvement in activity levels when treated with tezepelumab ...

Genome wide association studies (GWAS) have identified hundreds of genome regions containing thousands of genetic variants associated with asthma, but it’s still not clear which variants have an ...

“What we're trying to do is connect the dots between early life infections and ILC2s as the initial drivers of asthma susceptibility and asthma pathogenesis,” said Anna Beaudin, a hematopoietic stem ...

Asthma is a chronic respiratory condition marked by airway inflammation, narrowing, and episodes of wheezing, coughing, and shortness of breath. It affects millions of people worldwide and continues ...

Please provide your email address to receive an email when new articles are posted on . Sex and gender can influence the pathogenesis, clinical course, diagnosis, treatment and management of asthma, ...

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