Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin ...

In recent years, we have come to appreciate that loss or dysfunction of insulin-producing islet beta cells underlies virtually all major forms of diabetes mellitus. In type 1 diabetes, beta cells ...

Researchers have identified a specific hormone produced by pancreatic beta cells as a direct driver of obesity-linked pancreatic cancer in mouse models, shifting scientific attention away from insulin ...

Personalized therapies for diabetes, while showing promise in international studies, is met with healthy skepticism from ...

On March 16, Prof. James Lo, pharmacology cell and developmental biology, and his team published a study identifying different types of cells in the pancreas, an organ responsible for aiding digestion ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

Borrowing a cancer cell’s disguise, scientists shielded insulin-producing cells from attack by the immune system, a breakthrough that could pave the way for targeted type 1 diabetes treatments without ...

The beta cells in our pancreas act as highly sensitive sensors that constantly measure the amount of sugar in our blood. As ...

University of Chicago researchers developed an mRNA nanoparticle system that triggers cells to produce PD-L1 protein, potentially delaying type 1 diabetes progression in animal models.

The researchers investigated the impact of intermittent fasting on the beta cells. In the pancreas of mature mice, no negative effects on the beta cells were observed (here stained green). A recent ...