Calcium is the essential "on switch" for muscle contractions and a critical partner in maintaining hydration during hard ...

A new molecular pathway has been identified that is critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. Researchers at UMass Medical ...

The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...

IT is well established that an increase in the intracellular concentration of ionized calcium after excitation in the membrane is the key factor for initiation of contraction of various types of ...

The ability to modify the intracellular concentrations of divalent calcium ions is vital to normal cell functioning. In the cells of the cardiac muscle, calcium ions play a crucial role in coupling ...

The sarcomere is the most basic contractile unit in skeletal and cardiac muscle. Mutations in genes encoding sarcomeric proteins give rise to heritable myopathies, although muscle function is more ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...

Calcium is vital for bones, muscles, nerves, and heart health, and can be obtained from various non-dairy drinks.

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...