Receptors are generally transmembrane proteins, which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular switches to internal ...

Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

In this article, we take a look at eight biotechs that have acquired funding in recent years to fortify their GPCR-focused ...

Prostate cancer is the second most common cancer in men worldwide. Despite medical advances in recent years, this type of ...

New research from Scripps Research links Alzheimer’s disease and alcohol use disorder, showing similar gene expression ...

In a remarkable discovery, researchers have uncovered the key behind a traditional Asian medicine’s potential to combat ...

Reeves and his team have observed how cell signaling pathways drive cellular decision-making across different tissues and contexts. Signaling pathways such as the BMP pathway play important roles ...

In October, we think pink, and for a good reason-;one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening ...

The Cancer Cell Genomics, Signaling and Metastasis Research Program has four research aims, with a focus on lethal cancers in ...

These cells are known to respond to a variety of signaling pathways, but this study makes the case for BMP acting via binding to MuSK in maintaining the quiescent state. A central question in adult ...

Researchers discovered alcohol use disorder (AUD) and Alzheimer's disease (AD) exhibit similar patterns of gene dysregulation, hinting that alcohol consumption may hasten Alzheimer’s progression.

These findings suggest that KIR2DS2-positive (KIR2DS2+) natural killer (NK) cells could be an attractive therapeutic target ...