DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing ...

Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

The results of this collaborative project overturn some conventional wisdom about how the DNA repair process works. DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...