A protein called disrupted-in-schizophrenia 1, encoded by the DISC1 gene, has been established as a genetic risk factor for a wide array of psychiatric disorders, including schizophrenia, bipolar ...

The alternative text for this image may have been generated using AI. The current study examined the role of DISC1 in stress-induced PFC cognitive dysfunction. We explored whether knocking down Disc1 ...

Scientists now have a better understanding of a perplexing gene that is associated with susceptibility for a wide spectrum of severely debilitating mental illnesses. Two independent research studies ...

Researchers at Forschungszentrum Jülich in Germany have published two new studies offering fresh insight into a protein believed to play a pivotal role in the development of chronic mental health ...

Researchers have identified a protein that regulates a gene associated with schizophrenia. The study’s findings have significant implications for schizophrenia treatment. Researchers from the ...

Scientists are making progress towards a better understanding of the neuropathology associated with debilitating psychiatric illnesses like bipolar disorder and schizophrenia. New research, published ...

Disrupted-In-Schizophrenia-1 (DISC1), originally identified at the breakpoint of a chromosomal translocation that is linked to a rare familial schizophrenia, has been genetically implicated in ...

Scientists have for the first time shown how the disruption of a key gene involved in mental illness impacts on the brain. The discovery could be used in the future to help develop psychiatric drugs.

How much was previously known about the 'disrupted in schizophrenia-1' DISC-1 gene? The DISC-1 gene has been studied intensively over the years because people with mutations in DISC1 have a high ...

Researchers at MIT's Picower Institute for Learning and Memory have found that inhibiting a key brain enzyme in mice reversed schizophrenia-like symptoms. Researchers at MIT's Picower Institute for ...

DISC1 (disrupted-in-schizophrenia 1), originally identified in a large Scottish family suffering from multiple psychiatric disorders due to a chromosomal translocation-induced disruption, has been ...