The 2 x 2 factorial design has been advocated for improving the efficiency of clinical trials. Most such trials are designed on the assumption that there is no interaction between the levels of the ...
Effect of Breast Magnetic Resonance Imaging on the Clinical Management of Women With Early-Stage Breast Carcinoma PURPOSE: Factorial designs may be proposed to test extra questions within a clinical ...
This paper describes two level fractional factorial designs in which some of the treatment combinations are duplicated. As is well known, the duplicated runs provide ...