Fibrin formed as a result of fibrinogen polymerization is the main protein component of a clot in a test tube and intravascular thrombi in vivo. Fibrin clot structure characterized by fiber diameter ...

Blood clotting is the “Jekyll and Hyde” of biological processes. It’s a lifesaver when you’re bleeding, but gone awry, it causes heart attacks, strokes and other serious medical problems. If a clot ...

Despite improved diagnosis and treatment options, coronary artery disease (CAD) is still the leading cause of mortality and morbidity worldwide. Established risk factors such as smoking, ...

This scanning electron micrograph of a blood clot -- taken from the coronary artery of somebody who had a heart attack -- might be scary if it weren't so cool. Look closely: The brown mesh is a wiry ...

Fibrin plays a major role in stopping bleeding and healing wounds. However, if fibrin is formed in excess, e.g., in chronic wounds, thrombosis and subsequent vascular occlusions can occur. Therefore, ...

An antibody to the blood-clotting protein fibrin leaves coagulation alone but blocks the ensuing inflammatory cascade. Scientists led by Katerina Akassoglou, Gladstone Institutes, San Francisco, ...

The products of the blood clotting reaction, eg, thrombin and fibrinopeptides, have various proinflammatory activities and are suggested to modulate inflammation. The macrophage expression of tissue ...