A new study shows that RNA splicing, not just gene expression, holds powerful clues to why some mammals live far longer than ...
When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits ...
Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene "splicing" process, which happens ...
“This suggests that longer-lived species may have evolved molecular programs that optimize splicing for longevity, allowing ...
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...
The cover for issue 4 of Oncotarget features Figure 8, "Model for biological function categorization of PMEPA1 isoforms (c, d, and e) in the context of prostate cancer," by Sharad, et al. In addition ...
Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...
Pathogenic mutations within coding regions almost always change protein function. For a missense mutation in the DJ-1 gene that causes Parkinson’s disease, an entirely different mechanism may be at ...
HOUSTON (Oct. 17, 2005) – The gene responsible for Rett syndrome, a devastating neurological disease found mostly in girls, not only silences some genes but in combination with another also regulates ...