Scientists have created the most detailed cell map to date showing how genetic variation influences inflammatory bowel disease (IBD), revealing the specific cells and genes that drive the disease.

Genetic divergence and adaptive variation constitute the foundation of evolutionary change in natural populations. Divergence arises when populations accumulate distinct allele frequencies through ...

Genetic variation within Drosophila populations underpins our understanding of how organisms adapt to changing environments. As a premier model, Drosophila offers finely resolved genomic tools and ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Typically, the information encoded in DNA allows organisms to develop, function, and pass traits across generations. Yet DNA ...

Some variation is the result of differences in the surroundings, or what an individual does. This is called environmental variation. Humans, dogs and goldfish are examples of species. Different ...

Prostate cancer has distinct genetic properties in different groups of men that can be targeted to improve patient outcomes, UVA Cancer Center researchers have discovered. Based on new findings in ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

A new study suggests that the long-standing Mendelian view of genetics has some blind spots.

In the coming weeks, the Human Genome and Stem Cell Research Center (HUG-CELL) will begin recruiting participants for the ...