The need for large numbers of cells is not compatible with the iPSC processes and systems initially developed. To get these large numbers of cells, 3D systems are developed and used, culturing iPSCs ...

Human induced pluripotent stem cells (iPSCs) have a great potential for scientific and medical applications. They are used in ...

Mature iPSC-derived RPE cells are visible by super resolution confocal microscopy. One primary cilium resides in the center of each cell. RPE cell borders are stained showing tight junction markers.

Although induced pluripotent stem cell (iPSC)-derived midbrain organoids can recapitulate human ... They used a powerful imaging technique called 3D light sheet microscopy to visualize the complex ...

The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms.

A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor's surrounding ...

and investigation of new cell types for regenerative medicine purposes (human infant chondrocytes). Key words: hydrogel engineering, bioinks, 3D cartilage cultures, chondrocytes, human iPSc, 3D ...

iPS cells are being used to treat eye diseases to address donor shortages. We explore advancements made in Japan, such as the transplantation of iPS cell-derived corneal cells and retinal sheets.

Researchers led by Osaka University in Japan have conducted the first human trial using induced pluripotent stem-cell-derived ...

This research group has developed a robot/AI system that automatically performs trial-and-error to examine the optimum conditions for culturing iPS cells, and has ...

A new era of cell therapy has well and truly arrived with the iPSC field setting a trailblazing fire with its potential to develop fully scalable, off-the-shelf cell lines reducing the cost of ...