When most people think about insulin resistance, sugar is usually the first thing that comes to mind. And while excessive ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

As discussed above, there is considerable evidence from in vitro and in vivo studies that in a variety of tissues, hyperglycemia and possibly elevated FFA levels (both alone and in combination) result ...

Insulin resistance isn’t just about blood sugar—it’s a complex web of cellular, genetic, and lifestyle factors that impact your whole body. From inflammation to lipid buildup and even gut microbiome ...

Chronic hepatitis B (CHB) is a viral infection that affects many people in East London, particularly those from Bangladeshi, Pakistani, Chinese, African and Middle Eastern communities. These same ...

A large analysis uncovers new genetic pathways connecting lipid metabolites to cardiometabolic disease, enabling more precise ...

Small, consistent shifts in how and when you eat can support more stable hormonal health.

A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease, which includes heart disease, obesity and diabetes.