One of the most long-standing, fundamental mysteries of biology surrounds the poorly understood origins of introns. Introns are segments of noncoding DNA that must be removed from the genetic code ...

This is a preview. Log in through your library . Abstract Group I and II introns self-splice in vitro, but require proteins for efficient splicing in vivo, to stabilize the catalytically active RNA ...

This is a preview. Log in through your library . Abstract The gene encoding the small subunit rRNA serves as a prominent tool for the phylogenetic analysis and classification of Bacteria and Archaea ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor Protein-coding genes carry the blueprint for protein production. In higher ...

The sequences of nonsense DNA that interrupt genes could be far more important to the evolution of genomes than previously thought, according to researchers. Their study of the model organism Daphnia ...

Mysterious gene structures called introns that help make complex organisms possible are descended from DNA parasites that infested bacteria billions of years ago, according to a new study. Researchers ...

MicroRNAs (miRNAs) are the ∼22 nucleotide products of a two-step enzymatic maturation process facilitated by Drosha and Dicer, respectively 1. After biogenesis, the miRNA is then incorporated into the ...

Researchers have long puzzled over why many eukaryotic protein-coding genes are interspersed with segments of noncoding DNA that have no obvious biological function. These so-called introns are ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins. As human pre-mRNA introns vary in length ...