Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the ...

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells. However, many cancers can ...

Goto et al. 1 recently described a novel mechanism of immune evasion during the initial steps in the development of colorectal cancer in which nascent cancer cells reactivate a fetal program that is ...

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental factors and lifestyle, such as poor diet, sedentarism, obesity, smoking or ...

A surprising mechanism that makes some cancers treatment-resistant has been discovered by Weill Cornell Medicine and NewYork-Presbyterian investigators. The mechanism, which involves the shuttling of ...

Tsukuba, Japan—In Japan, cancer has been the leading cause of death since 1981. At present, surgery, chemotherapy, and radiotherapy are the main treatment options. However, these treatments ...

Researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer. LMU researchers have discovered how the interplay ...