In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.

New research, led by LJI scientists, offers a potential way to boost tissue-resident memory T cell numbers to better fight disease.

Memory T cells are a special type of white blood cell that "remember" past infections and vaccines, helping our bodies to ...

Vijay K. Kuchroo, PhD, DVM, of the Gene Lay Institute of Immunology and Inflammationof Brigham and Women’s Hospital, Massachusetts General Hospital and Harvard Medical School and the Ann Romney Center ...

Dr. André Ballesteros-Tato received his Ph.D. in Molecular Biology from the Autonoma University of Madrid in Spain in July 2007. For his thesis work, he studied the role of the cell cycle inhibitor, ...

For decades, dogma dictated that the immune system consisted of two separate branches. Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Now Vijayanand and his colleagues have discovered the cellular driver that leads to T RM cell development. Their findings, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 18 (May 3, 2022), pp. 1-12 (12 pages) B and T lymphocytes of the adaptive immune system undergo ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...