Senescent fibroblasts are aging cells that no longer divide and protect against tumor development. Yet two decades have gone ...

The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...

Noncancerous tissue (stroma) surrounding cancers of the throat and cervix play an important role in regulating the spread of cancer cells, according to researchers at Queen's University in Belfast, ...

The tumour–stroma ratio (TSR) is emerging as a robust, cost‐effective histopathological parameter that quantifies the relative proportion of neoplastic cells to the surrounding stromal tissue.

Relationship of pro-angiogenic factor Cyr61to colorectal cancer development and prognosis. Background: Microarrays are widely used to study gene expression patterns in cancer. In colorectal cancer, it ...

A recent study found that tumor-stroma proportion was a reliable marker of chemoresistance, progression-free survival, and overall survival in high-grade serous ovarian cancer. TSP, which assesses the ...

—In this study, molecular classification of endometrial cancer with cervical stromal invasion was associated with recurrence-free survival by univariate analysis. But after controlling for tumor stage ...

Cancer of the immune system, called lymphoma or leukaemia, generally affects the entire body’s bone marrow and lymph nodes. Because these types of cancers are so widespread, surgery isn’t useful, so ...

GISTs are solid tumors, primarily in the stomach, characterized by KIT and EGFR mutations, with Gleevec as a key treatment.