They observed that “CD4+CD25+ T regulatory cells were much more likely to adhere to TECs versus NECs,” suggesting that immunosuppressive T cells are allowed to bypass the TEC barrier and enter the ...

Background: Tec (JNJ-64007957) is a BCMA x CD3 bispecific antibody (Ab) that redirects CD3+ T cells to mediate T-cell activation and subsequent lysis of BCMA-expressing myeloma cells. MajesTEC-1 is a ...