Many patients suffer from epilepsy that cannot be controlled by current medications. Surgical removal of epileptogenic brain regions is effective in only about half of cases, and not all patients are ...

Boosting KCC2 function reduced seizures and abnormal brain activity in temporal lobe epilepsy models. Learn how this strategy could aid drug-resistant epilepsy.

Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from ...

Researchers identify prochlorperazine as a potential new treatment for temporal lobe epilepsy by restoring the KCC2 chloride ...

Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from ...

Epileptic activity originating from one or more diseased brain regions in the temporal lobe is difficult to contain. Many patients with so-called temporal lobe epilepsy often do not respond to ...

The prognostic value of exact location of hypometabolism measured by PET within the temporal lobe is still debating. Some studies suggested that patients with mesial temporal hypometabolism on PET ...

Experimental activation of a small set of nerve cells in the brain prevents convulsive seizures in a mouse model of temporal lobe epilepsy, the most common form of epilepsy among human adults.

In a retrospective cohort, a clinical heuristic composed of eight binary variables helped identify which patients with medial temporal lobe epilepsy (MTLE) were best suited for stereotactic laser ...

The present study was designed to evaluate the genetic mechanisms in patients with focal epileptiform discharges in the mid-temporal or central regions, an electroencephalographic abnormality of high ...

Kuzniecky et al. expressed concerns about the differences between normal aging-related cerebral atrophy observed in our healthy controls and those reported in a previous study, which showed widespread ...