He means that when you sit down at your computer, you typically use the Start button to begin your computing session, but in the future, you'll sit down and open Copilot instead.

Microsoft moved the Start button in Windows 11, but you can move it back with a few clicks.

Could Microsoft phase out the Start button in Windows 12 and replace it with Copilot? Listen to Microsoft CEO Satya Nadella, and it seems like a very real possibility.