BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

The increasing demand for donor hearts presents both a critical challenge and a significant opportunity for innovation in ...

Cardiovascular disease (CVD) mortality increased by 78%, rising from 72.4 to 128.7 per 100 000 (2017–2022), with the greatest ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

A cardiac catheterization takes ≈45 minutes to complete. After a coronary angiogram, depending on the severity and pattern of any blockages detected in the coronary arteries, 3 common treatment paths ...

Despite decades of technique refinement of transarterial embolization and the establishment of specialty referral centers, fetuses diagnosed with vein of Galen malformation continue to have high ...

Gene Ontology analysis from differentially expressed genes revealed expected changes in cell cycle, metabolism, and contractility. In addition, mRNA splicing was among the top enriched differentially ...

According to criteria established by the AHA/NHLBI and published in Circulation (Circulation. 2005;112:2735–2752).

Left ventricular (LV) systolic function is a powerful prognosticator of clinical outcome following percutaneous coronary intervention (PCI), 1, 2, 3 and patients who do not have in‐hospital LV ...

A total of 8 canines, with a weight of 35 to 40 kg and an age of 2.90±0.56 years, were randomized after the surgical procedure by the weight order into 2 observation groups: a 48-hour group (N=4) and ...

We conducted a US‐based cost‐effectiveness analysis of dapagliflozin added to standard of care in a chronic heart failure population using pooled, participant data from the DAPA‐HF (Dapagliflozin and ...