This article explores how to generate high-quality transcriptomics data by optimizing each step, from experimental design and RNA extraction to library preparation sequencing and data analysis, to ...

This valuable study analyzes aging-related chromatin changes through the lens of intra-chromosomal gene correlation length, which is a novel computational metric that captures spatial correlations in ...

The world of cells is surprisingly noisy. Each cell carries unique genetic information, but when we try to measure cellular ...

Single-cell RNA sequencing (scRNA-seq) has revolutionized modern biology, allowing scientists to study the expression of genes from thousands of individual cells at the same time. This technique helps ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...