One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The human genome is no longer just a sequence to be read. It’s a dynamic structure that twists, folds, and reshapes itself in ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Visualization of the genome (green) and a single gene (magenta) in a human cell nucleus, with genomic motions mapped by arrows and an example of a gene trajectory highlighted as a colored curve. A ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Research shows synthetic chromosomes can be transferred to human cells with potential to improve viral resistance ...

Some of the incredible complexity underlying the genome is understood. For example, the effects of chromatin remodeling on gene expression. However, the implications of the movements that occur during ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...