Objective Live biotherapeutic products (LBPs) are biological products composed of living micro-organisms, developed to ...

Over the past few decades, the prevalence of chronic inflammatory and metabolic diseases has risen sharply, coinciding with significant environmental and lifestyle changes. While genetics play a role, ...

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

Introduction The Joint Advisory Group (JAG) ISREE initiative in 2019 called for an improvement of safety in endoscopy, one of the recommendations was simulation training for staff. Endoscopy ...

Objective Early-onset colorectal cancer (CRC) is increasing in the USA despite rapid declines in older ages. Similar patterns are reported in Australia and Canada, but a comprehensive global analysis ...

Objective Autophagy participates in the progression of hepatocellular carcinoma (HCC) and the resistance of HCC cells to sorafenib. We investigated the feasibility of sensitising HCC cells to ...

Correspondence to Dr Citadel J Cabasag, Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France; cabasagc{at}fellows.iarc.fr We read with interest the commentary by ...

We have studied 22 consecutive patients referred for investigation of severe chronic right upper quadrant pain. The majority were women whose symptoms had been present for many years. All had ...

Background—RNA sequences of the recently identified hepatitis GB virus C (HGBV-C), also named hepatitis G virus (HGV), have been detected in patients with idiopathic fulminant hepatic failure (FHF) ...

Introduction Non-alcoholic fatty liver disease (NAFLD) affects approximately 1 in 4 adults in the UK. 1 In our hospital catchment area there are an estimated 150000 individuals with NAFLD, ...

Objective Artificial intelligence (AI) may reduce underdiagnosed or overlooked upper GI (UGI) neoplastic and preneoplastic conditions, due to subtle appearance and low disease prevalence. Only disease ...

Introduction As clinicians we are taught to assess all patients for cutaneous signs of chronic liver disease (CLD). However, there is limited evidence available in the literature regarding their ...