Could this mark a shift in how we think about cancer therapy? At least in the laboratory, evidence suggests it may be.

Among patients with idiopathic pulmonary fibrosis, the risk for all-cause mortality was significantly lower with vs. without ...

Some medications, including certain antibiotics and NSAIDs, can harm the kidneys if used for too long or in high doses. ACE inhibitors and ARBs are generally safe but can increase the risk of kidney ...

A new FDA approval for a first-in-class drug has vaulted Otsuka into immunoglobulin A nephropathy (IgAN), an increasingly competitive kidney disease field targeted by multiple biopharma companies. The ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on how pancreatic cancer cells resist treatment and points to potential new combination therapies to make treatments ...

The use of proton pump inhibitors with anti-cancer therapies was associated with worse survival outcomes in patients with breast cancer. Concomitant use of proton pump inhibitors and other everyday ...

Panelists discuss how ARNIs like sacubitril-valsartan provide superior outcomes compared with ACE inhibitors in HFrEF (20% reduction in cardiovascular events, 16% mortality reduction), with broad FDA ...

Angiotensin I-converting enzyme (ACE) inhibition has revolutionised cardiovascular care, yet classical inhibitors face safety and efficacy challenges. Here, Professors Ravi Acharya and Edward Sturrock ...

Background: Anthracyclines are essential components of chemotherapeutic regimens for a broad spectrum of malignancies, yet their utility is constrained by cumulative, dose-dependent cardiotoxicity, ...

Angiotensin converting enzyme (ACE) inhibitors, a type of blood pressure medication, are usually well tolerated, but one of their rare side effects is angioedema. Angiotensin converting enzyme (ACE) ...

ICIs, representing a revolutionary breakthrough in cancer immunotherapy, restore T-cell antitumor activity by targeting and blocking inhibitory immune molecules, thereby significantly extending the ...