CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has been extremely effective ...

Cellular therapies, including TIL, TCR, and CAR-T, are transforming lung cancer care by utilizing personalized immune cells to target tumors. TIL therapy, now FDA-approved for solid tumors, shows ...

Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make ...

Like all hardworking things, the cytotoxic T lymphocytes (CTLs) of the immune system charged with detecting and destroying cancer cells tend to get very tired—so much so, in fact, that they can even ...

Cell therapies, which have made waves in the treatment of blood cancer, are showing potential for solid tumors.

Blocking a single protein revs up T cells, boosting their energy reserves and helping them fight tumors longer in new mouse ...

New research shows lymph nodes aren’t just cancer bystanders, they’re the command centers fueling immune attacks. Surgically removing them along with tumors may weaken treatment, while preserving them ...

A new nanoparticle vaccine successfully prevented several aggressive cancers in mice, including pancreatic and melanoma. The ...

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells ...