Abstract. In recent years, accumulation of mitochondrial reactive oxygen species (ROS) has been shown to limit the proliferative capacity and intratumoral persistence of CD8+ T cells, but the ...

Department of Physiology, University of Kentucky Schoof of Medicine, Lexington, Kentucky. *Corresponding Author: Erhard Bieberich, Department of Physiology, University of Kentucky College of Medicine, ...

1Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina. 2Hollings Cancer Center, Medical University of South Carolina, Charleston, South ...

Cancer Biology Evolution Program, Integrated Mathematic Oncology Department, Radiology Department, Moffitt Cancer Center, Tampa, Florida. *Corresponding Author: Robert A. Gatenby, Cancer Biology ...

1Centre for Computational Biology, Duke-NUS Medical School, Singapore ...

*Corresponding Author: Anne McTiernan, Public Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Avenue North, P.O. Box 19024, Seattle, WA 98109. E-mail: [email protected] ...

1Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, Freiburg University Medical Center, Freiburg, Germany.

Abstract. Platinum-resistant ovarian cancer remains one of the greatest challenges in oncology, with limited treatment options and poor survival outcomes. To address this unmet need we develop MDC-735 ...

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Suzhou Genhouse Pharmaceutical Co., Ltd., Suzhou, China.

Creighton University School of Medicine, Omaha, NE.

Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York ...