This animation shows the ligand-gated ion channel GABA_A. GABA binds to the extracellular portion of the GABA_A receptor. This causes a conformational change of the GABA_A receptor which leads to the opening of the channel. Chloride ions (green) can then rush into the cell. | Ribosome Studio
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This animation shows the ligand-gated ion channel GABA_A. GAB…
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The GABA-B receptor functions as a neuronal inhibitor, distinct from its counterpart, the GABA-A receptor. It operates as a G-protein-coupled receptor (GPCR), meaning that upon activation, it initiates a cellular signaling cascade rather than acting as a direct ion channel. When a signal molecule binds, the receptor releases its associated G-protein. The G-beta-gamma subunit then travels through the cell to activate a specific type of potassium channel called GIRK (G-protein-gated inwardly recti
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